Searchable abstracts of presentations at key conferences in endocrinology

ea0011p922 | Thyroid | ECE2006

The distance between histotypes of differentiated thyroid cancer: gene expression profiling study

Jarzab B , Wloch J , Lange D , Oczko-Wojciechowska M , Chmielik E , Czarniecka A , Kowalska M , Fujarewicz K , Simek K , Gala G , Swierniak A

We apply the oligonucleotide microarray technology to study the expression profile of differentiated thyroid cancer (DTC) and to select transcripts which differentiate between its subclasses. We use state-of-the-art bioinformatic techniques, based on Support Vector Machines algorithms, to select not only the single ‘solitary’ markers but rather the sets of genes which are taken into account cooperatively to enhance the diagnosis accuracy. Simultaneously, we try to me...